Ureaplasma in pregnancy and in newborns

Ureaplasma infection during pregnancy can pose significant risks to both mother and baby.

Ureaplasmas are part of the normal bacterial flora of the urogenital tract and usually do not cause symptoms. However, ureaplasma infection in pregnant women and newborns can have serious consequences.

Ureaplasma in pregnancy

The presence of ureaplasma during pregnancy can increase the risk of a number of complications, for example:

  • chorioamnionitis
  • premature rupture of the amniotic sac
  • premature birth.

Chorioamnionitis is an infection that affects the chorion, amnion, and amniotic fluid around the fetus. Ureaplasma can penetrate from the vagina into the uterus and cause inflammation of the membranes of the amniotic sac and amniotic fluid. As a result, the rupture of the membranes increases and the risk of premature rupture of the amniotic sac – rupture of the amniotic sac before 37 weeks of gestation. This can lead to a number of complications, including: premature birth, umbilical cord prolapse, placental abruption, and more.

The presence of ureaplasma in the amniotic fluid induces the production of cytokines, prostaglandins, uterine contractions, dilatation of the cervix, potentially contributing to premature birth.

Ureaplasma infection is also associated with an increased risk of postpartum endometritis – inflammation of the lining of the uterus. However, the relationship is not firmly established.

Ureaplasma in newborns

Ureaplasmas can be isolated from the respiratory tract of newborns. The degree of isolation correlates with the weight of the baby at birth – premature babies are infected much more often than full-term babies. Colonization decreases after 3 months of age.

Ureaplasma infection in newborns carries the following risks:

  • low birth weight

Babies born to mothers with ureaplasma infection may have a lower birth weight. Low birth weight is associated with a higher risk of health problems.

  • neonatal sepsis

Newborns have a poorly developed immune system and can develop sepsis – ureaplasmas get into the blood and spread throughout the body. Neonatal sepsis can be life-threatening and requires immediate treatment.

  • bronchopulmonary dysplasia

Ureaplasma is associated with a risk of bronchopulmonary dysplasia, especially in premature infants. Bronchopulmonary dysplasia is a chronic lung disease that results from lung damage caused by mechanical ventilation and long-term oxygen therapy.

  • pneumonia – newborns infected with ureaplasma can develop pneumonia, which can be serious and require intensive medical care.
  • meningitis – in rare cases, ureaplasma can cause meningitis (inflammation of the membranes around the brain and spinal cord) in newborns. This condition requires immediate medical attention.


Abbas Jahangir

I am a researcher and writer with a background in food and nutritional science. I am the founder of Foodstrend.com, our reputable online platform offering scientifically-backed articles on health, food, nutrition, kitchen tips, recipes, diet, and fitness. With a commitment to providing accurate and reliable information, we strive to empower our readers to make informed decisions about their health and lifestyle choices. Join us on Foodstrend.com's journey toward a healthier and happier lifestyle.

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